diff --git a/dataset-index.yml b/dataset-index.yml
index 984d34a6..8bb51dd6 100644
--- a/dataset-index.yml
+++ b/dataset-index.yml
@@ -719,6 +719,12 @@
     paper: https://arxiv.org/pdf/2009.03300
     configpath: opencompass/configs/datasets/mmlu/mmlu_gen.py
     configpath_llmjudge: opencompass/configs/datasets/mmlu/mmlu_llm_judge_gen.py
+- PromptCBLUE:
+    name: PromptCBLUE
+    category: Understanding
+    paper: https://arxiv.org/pdf/2310.14151
+    configpath: opencompass/configs/datasets/PromptCBLUE/PromptCBLUE_gen.py
+    configpath_llmjudge: opencompass/configs/datasets/PromptCBLUE/PromptCBLUE_llmjudge_gen.py
 - mmlu_cf:
     name: MMLU-CF
     category: Understanding
diff --git a/opencompass/configs/datasets/PromptCBLUE/PromptCBLUE_0shot_gen_b1eb29.py b/opencompass/configs/datasets/PromptCBLUE/PromptCBLUE_0shot_gen_b1eb29.py
new file mode 100644
index 00000000..2480a4b6
--- /dev/null
+++ b/opencompass/configs/datasets/PromptCBLUE/PromptCBLUE_0shot_gen_b1eb29.py
@@ -0,0 +1,64 @@
+from opencompass.openicl.icl_prompt_template import PromptTemplate
+from opencompass.openicl.icl_retriever import ZeroRetriever
+from opencompass.openicl.icl_inferencer import GenInferencer
+from opencompass.openicl.icl_evaluator import AccEvaluator
+from opencompass.utils.text_postprocessors import first_capital_postprocess
+from opencompass.datasets import PromptCBLUEDataset
+
+# 1. 子数据集名称
+PromptCBLUE_lifescience_sets = [
+    'CHIP-CDN', 'CHIP-CTC', 'KUAKE-QIC', 'IMCS-V2-DAC',
+    'CHIP-STS', 'KUAKE-QQR', 'KUAKE-IR', 'KUAKE-QTR'
+]
+
+# 2. Reader 配置
+reader_cfg = dict(
+    input_columns=['input', 'answer_choices', 'options_str'],
+    output_column='target',
+    train_split='validation',
+)
+
+# 3. Prompt 模板：末行固定 ANSWER: $LETTER
+_HINT = 'Given the ICD-10 candidate terms below, choose the normalized term(s) matching the original diagnosis.'
+
+query_template = f"""{_HINT}
+
+Original diagnosis: {{input}}
+
+Options:
+{{options_str}}
+
+The last line of your response must be exactly:
+ANSWER: $LETTER
+""".strip()
+
+infer_cfg_common = dict(
+    prompt_template=dict(
+        type=PromptTemplate,
+        template=dict(round=[dict(role='HUMAN', prompt=query_template)]),
+    ),
+    retriever=dict(type=ZeroRetriever),
+    inferencer=dict(type=GenInferencer),
+)
+
+# 4. 评估配置
+eval_cfg_common = dict(
+    evaluator=dict(type=AccEvaluator),
+    pred_postprocessor=dict(type=first_capital_postprocess),
+)
+
+# 5. 组装数据集配置
+promptcblue_datasets = []
+for ds_name in PromptCBLUE_lifescience_sets:
+    promptcblue_datasets.append(dict(
+        abbr=f'promptcblue_{ds_name.lower().replace("-", "_")}_norm',
+        type=PromptCBLUEDataset,
+        path='tchenglv/PromptCBLUE',
+        name=ds_name,
+        reader_cfg=reader_cfg,
+        infer_cfg=infer_cfg_common,
+        eval_cfg=eval_cfg_common,
+    ))
+
+# ★ OpenCompass 识别的出口变量
+datasets = promptcblue_datasets
diff --git a/opencompass/configs/datasets/PromptCBLUE/PromptCBLUE_0shot_llmjudge_gen_2ee607.py b/opencompass/configs/datasets/PromptCBLUE/PromptCBLUE_0shot_llmjudge_gen_2ee607.py
new file mode 100644
index 00000000..cf2d8e43
--- /dev/null
+++ b/opencompass/configs/datasets/PromptCBLUE/PromptCBLUE_0shot_llmjudge_gen_2ee607.py
@@ -0,0 +1,102 @@
+from opencompass.openicl.icl_prompt_template import PromptTemplate
+from opencompass.openicl.icl_retriever import ZeroRetriever
+from opencompass.openicl.icl_inferencer import GenInferencer
+from opencompass.openicl.icl_evaluator import AccEvaluator
+from opencompass.evaluator import GenericLLMEvaluator
+from opencompass.datasets import generic_llmjudge_postprocess
+from opencompass.datasets import PromptCBLUEDataset
+
+PromptCBLUE_lifescience_sets = [
+    'CHIP-CDN', 'CHIP-CTC', 'KUAKE-QIC', 'IMCS-V2-DAC',
+    'CHIP-STS', 'KUAKE-QQR', 'KUAKE-IR', 'KUAKE-QTR'
+]
+# Query template (keep original)
+QUERY_TEMPLATE = """
+Given a medical diagnosis description and labeled ICD-10 candidate terms below, select the matching normalized term(s).
+Original diagnosis: {input}
+
+Options:
+{options_str}
+
+The last line of your response must be exactly in the format:
+ANSWER: <LETTER(S)>
+""".strip()
+
+# Grader template (keep original)
+GRADER_TEMPLATE = """
+As an expert evaluator, judge whether the candidate's answer matches the gold standard below.
+Return 'A' for CORRECT or 'B' for INCORRECT, with no additional text.
+
+Original diagnosis: {input}
+
+Options:
+{options_str}
+
+Gold answer: {target}
+
+Candidate answer: {prediction}
+""".strip()
+
+# Common reader config
+reader_cfg = dict(
+    input_columns=['input', 'answer_choices', 'options_str'],
+    output_column='target',
+    train_split='validation'
+)
+
+# Assemble LLM evaluation datasets
+promptcblue_llm_datasets = []
+for name in PromptCBLUE_lifescience_sets:
+    infer_cfg = dict(
+        prompt_template=dict(
+            type=PromptTemplate,
+            template=dict(round=[
+                dict(role='HUMAN', prompt=QUERY_TEMPLATE),
+            ]),
+        ),
+        retriever=dict(type=ZeroRetriever),
+        inferencer=dict(type=GenInferencer),
+    )
+
+    eval_cfg = dict(
+        evaluator=dict(
+            type=GenericLLMEvaluator,
+            prompt_template=dict(
+                type=PromptTemplate,
+                template=dict(
+                    begin=[
+                        dict(
+                            role='SYSTEM',
+                            fallback_role='HUMAN',
+                            prompt='You are an expert judge for medical term normalization tasks.',
+                        )
+                    ],
+                    round=[
+                        dict(role='HUMAN', prompt=GRADER_TEMPLATE),
+                    ],
+                )
+            ),
+            dataset_cfg=dict(
+                type=PromptCBLUEDataset,
+                path='tchenglv/PromptCBLUE',
+                name=name,
+                reader_cfg=reader_cfg,
+            ),
+            judge_cfg=dict(),
+            dict_postprocessor=dict(type=generic_llmjudge_postprocess),
+        ),
+        pred_role='BOT',
+    )
+
+    promptcblue_llm_datasets.append(
+        dict(
+            abbr=f"promptcblue_{name.lower().replace('-', '_')}_norm_llm",
+            type=PromptCBLUEDataset,
+            path='tchenglv/PromptCBLUE',
+            name=name,
+            reader_cfg=reader_cfg,
+            infer_cfg=infer_cfg,
+            eval_cfg=eval_cfg,
+            mode='singlescore',
+        )
+    )
diff --git a/opencompass/configs/datasets/PromptCBLUE/README.md b/opencompass/configs/datasets/PromptCBLUE/README.md
new file mode 100644
index 00000000..e69de29b
diff --git a/opencompass/datasets/PromptCBLUE.py b/opencompass/datasets/PromptCBLUE.py
new file mode 100644
index 00000000..3266c6ea
--- /dev/null
+++ b/opencompass/datasets/PromptCBLUE.py
@@ -0,0 +1,62 @@
+from datasets import Dataset, DatasetDict, load_dataset
+
+from opencompass.registry import LOAD_DATASET
+
+from .base import BaseDataset  # 保持与 MMLUDataset 同级的导包风格
+
+
+@LOAD_DATASET.register_module()
+class PromptCBLUEDataset(BaseDataset):
+    """Loader for PromptCBLUE life-science tasks (CHIP-CDN, CHIP-CTC …).
+
+    - 只读 validation split。
+    - 保留指定 `task_dataset` 的所有任务类型。
+    - 若 `target` 不在 `answer_choices`，自动追加；并生成 `options_str`。
+    - 返回 `DatasetDict`，包含 `validation` 和 `test`，以满足评估流程。
+    """
+
+    @staticmethod
+    def load(path: str, name: str, **kwargs):
+        # 1) 从 HuggingFace 读取 validation split
+        hf_ds = load_dataset(path, split='validation', **kwargs)
+
+        # 2) 过滤子数据集并构造记录
+        records = []
+        for rec in hf_ds:
+            if rec.get('task_dataset') != name:
+                continue
+
+            choices = rec.get('answer_choices', []).copy()
+            target = rec.get('target')
+            if target not in choices:
+                choices.append(target)
+
+            options_str = '\n'.join(f'{chr(65 + i)}. {opt}'
+                                    for i, opt in enumerate(choices))
+
+            records.append({
+                'input': rec['input'],
+                'answer_choices': choices,
+                'options_str': options_str,
+                'target': target,
+            })
+
+        # 3) 构造 Dataset
+        if records:
+            validation_ds = Dataset.from_list(records)
+        else:
+            validation_ds = Dataset.from_dict({
+                k: []
+                for k in [
+                    'input',
+                    'answer_choices',
+                    'options_str',
+                    'target',
+                ]
+            })
+
+        # 4) 返回时包含 validation 和 test
+        return DatasetDict(
+            validation=validation_ds,
+            test=validation_ds,
+        )
diff --git a/opencompass/datasets/__init__.py b/opencompass/datasets/__init__.py
index dfbc20ca..9992c4b3 100644
--- a/opencompass/datasets/__init__.py
+++ b/opencompass/datasets/__init__.py
@@ -125,6 +125,7 @@ from .OlympiadBench import *  # noqa: F401, F403
 from .OpenFinData import *  # noqa: F401, F403
 from .physics import *  # noqa: F401, F403
 from .piqa import *  # noqa: F401, F403
+from .PromptCBLUE import *  # noqa: F401, F403
 from .ProteinLMBench import *  # noqa: F401, F403
 from .py150 import *  # noqa: F401, F403
 from .qasper import *  # noqa: F401, F403